Fluorescent Analogs of Biomolecular Building Blocks: Design, Properties, and Applications
نویسندگان
چکیده
منابع مشابه
Rational design of hetero-ring-expanded guanine analogs with enhanced properties for modified DNA building blocks.
The properties and modes of recognition of physiological DNAs associated with the four natural nucleobases might be extended, in principle, by the design of non-natural nucleobase derivatives. The goal is an expansion of the genetic alphabet, with the possible outcome of producing new DNAs with improved physical or biological properties. In this work, a new series of hetero-ring-expanded guanin...
متن کاملMicrowave spectroscopy of biomolecular building blocks.
Microwave spectroscopy, considered as the most definitive gas phase structural probe, is able to distinguish between different conformational structures of a molecule, because they have unique spectroscopic constants and give rise to distinct individual rotational spectra.Previously, application of this technique was limited to molecular specimens possessing appreciable vapor pressures, thus di...
متن کاملGas-phase spectroscopy of biomolecular building blocks.
Gas-phase spectroscopy lends itself ideally to the study of isolated molecules and provides important data for comparison with theory. In recent years, we have seen enormous progress in the study of biomolecular building blocks in the gas phase. The motivation for such work is threefold: (a) It is important to distinguish between intrinsic molecular properties and properties that result from th...
متن کاملPREPARATION AND APPLICATIONS OF FLUORESCENT POLYGLUTARALDEHYDE IMMUNOMICROSPHERES
Aqueous glutaraldehyde has been polymerized under alkaline conditions in the presence of a surfactant to yield microspheres of varied diameters. Microbeads of a nominal 300 nm diameter, made fluorescent via fluoresceinisothiocyanate, were used as a carrier of rabbit anti-human red blood cell antibodies. Specific labeling of the human red blood cells as well as diagnostic use of these fluor...
متن کاملBuilding Blocks for Agent Design
We present our Component-Based Agent Framework, which enables a software engineer to design a set of agents by using a visual compo nent-based toolkit (Sun’s BDK), and wiring together desired blocks of functionality. We instantiate this framework in the RoboCup domain by implementing the necessary components. The implementation also serves as a proof of the viability of our framework. Finally, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Reviews
سال: 2010
ISSN: 0009-2665,1520-6890
DOI: 10.1021/cr900301e